It was reported earlier this week that Mitchell underwent a “small procedure” on the finger he injured in practice ahead of Week 3. Given that news, it doesn’t come as much of a surprise to learn that Mitchell will miss his fourth straight game with the injury. With rookie Omar Cooper Jr. set to play in his first game since Week 1, Mitchell could face additional competition for targets when he finally returns to the field.
Slayton signed with the Colts less than a month ago but never suited up for the team on game day. The 29-year-old speedster was briefly considered as a candidate to replace Alec Pierce (foot), but he’s once again on the open market in search of work. A knee injury resulted in Slayton being scratched from Week 5’s matchup against the Steelers, so it’s possible he’ll have to prove he’s healthy before signing elsewhere this season.
Shaheed’s eight targets were a product of 51 Sam Darnold pass attempts in a game the Seahawks could not find any room to run on the ground. He lost a fumble on a fluke play in the second quarter in which he rolled over the tackling defender, only for the defender’s knee to knock the football loose before Shaheed’s rear end touched the playing surface. he would fumble a punt return in the fourth quarter but easily had time to regain control before the ball was in real trouble. Shaheed remains the third option through the air for an offense typically not seeing this level of volume, making him a touchdown-or-bust fantasy option, for the time being. That doesn’t change ahead of a Week 6 meeting with the Chiefs in Seattle.
Kupp’s 10 targets finished second on the team behind alpha Jaxon Smith-Njigba but were largely a product of 51 Sam Darnold pass attempts in game that had all the ingredients for increased pass volume, including an inability to run the football, negative game script, and overtime. It continues to appear as if Kupp’s fantasy-relevant days are far behind him, with the veteran best left on the waiver wire ahead of a Week 7 showdown against the Chiefs on deck.
The Broncos managed just 168 yards of total offense on a night their defense carried them to victory in overtime. Nine of the Broncos’ 11 possessions, excluding the two kneel downs to end each half, ended in punts on drives that lasted five plays or fewer. Two second quarter touchdown drives had the Broncos playing with a lead for much of the game but they were otherwise unable to move the football with any consistency. An overtime interception by nickel corner Ja’Quan McMillian allowed for a game-winning, 53-yard field goal from kicker Will Lutz after the Broncos again failed to gain a first down. The win sends Denver to 4-2 while averaging only 18.7 points per game through six weeks. The team gets a scheduling gift with the Cardinals on deck in Week 7, although Nix cannot be treated as a starter-worthy fantasy asset outside of the deepest leagues.
Dobbins found little room to run on a night the Broncos gained only 168 yards of total offense but handily led the backfield in opportunities in what was a consistently positive game script due to the dominance of their defense. Dobbins has now failed to eclipse a modest 50 yards on the ground in four of five appearances but might be useful as a bye week fill-in when the Broncos travel to Arizona to face the Cardinals in Week 7.
The fact that the 31 yards through the air led the team in receiving is a comment on the state of an offense that gained only 168 yards of total offense against the defending Super Bowl Champions. Even so, a relentlessly aggressive defense willed the team to victory behind a consistently positive game script, which allowed J.K. Dobbins to handily lead the backfield in opportunities. Harvey remains a matchup-dependent fantasy option best utilized in trailing game environments, which is unlikely to be the case when the Broncos face the struggling Cardinals in Week 7.
Nix’s only incompletion when targeting Sutton resulted in the veteran receiver getting rocked over the middle of the field on a ball Nix led him directly into oncoming contact. Sutton vented his frustration by repeatedly pounding the ground following the hit, with it unclear whether it was due to the hit or the incompletion on third down on a night the Broncos struggled to move the football to the tune of only 168 yards of total offense. Fantasy managers likely aren’t utilizing Sutton as a weekly option, but will want to track his practice status ahead of a Week 7 meeting with the Cardinals if bye week fill-ins are required.
Engram has not seen more than five targets in a game this season and has been held out of the end zone since Week 1, making him a difficult start in fantasy leagues of all sizes. He can safely remain on the bench in an enticing matchup against the Cardinals in Week 7.
The Seahawks struggled to move the football throughout against the tenacious situational play calling from Broncos defensive coordinator Vance Joseph, scoring only three points until just over five minutes remaining in the fourth quarter. A late-game surge saw them punch on in and a successful two-point conversion drew the team within three points. They would stop the Broncos on the subsequent possession but an interception in Denver territory put the game in jeopardy. The defense would do their job and force a three-and-out that took only 15 seconds off the clock, giving the ball back to Darnold to lead a two-minute drill to send the game to overtime through a chip shot field goal. Darnold would throw his second interception in overtime, watching from the sideline as the Broncos walked it off with a 53-yard Will Lutz field goal. The loss sends the Seahawks to 3-3, matching the total number of losses from a season ago through only six weeks of the 2026 season. The Seahawks have work to do to make up ground in the NFC West, now 2.5 games behind the undefeated 49ers through the first third of the regular season. Darnold and the Seahawks now have a long week to prepare for the now-undefeated Chiefs at home in Week 7, where Darnold will be a fringe QB2 in fantasy circles.
Wilson is now down to just 3.4 yards per carry while filling in for numerous key injuries in the Seattle backfield, with the team clearly waiting with bated breath for the return of Zach Charbonnet. Charbonnet continues to inch closer to a return from injured reserve and appears likely to bring an end to the Wilson experiment, relegating the latter to bench fodder in fantasy circles in the process. That could come a early a Week 7 when the Seahawks host the Chiefs.
Holani split primary change of pace duties with recent practice squad call-up Velus Jones Jr, the latter of whom turned four carries into 20 yards while losing one yard on his lone reception. Both backs appear unlikely to return fantasy value as Zach Charbonnet nears a return from injured reserve.
Smith-Njigba overcame a sluggish first half to extend his stranglehold on the overall WR1 in fantasy circles with a dominant second half and overtime period. While the 51 pass attempts from Sam Darnold were highly uncharacteristic of this Seattle offense, a complete inability to run the football paired with a negative script to form the perfect environment for Smith-Njigba to set a season high in targets and receptions. Smith-Njigba has now gone over 100 yards in five of six appearances to start the 2026 regular season and is in a good spot to continue that dominance when the Seahawks host the Chiefs in Week 7, where he remains a top-tier WR1 in fantasy circles.
Waddle departed early in the third quarter and was quickly deemed questionable to return with a shoulder injury. It is unclear when the injury occurred. Waddle managed to catch just 2-of-5 targets for 15 yards prior to departing, keeping his usable weeks total at just two games through the first six weeks of the 2026 season. Fantasy managers that invested a fourth-round pick on the veteran wide receiver have got to begin to make alternate plans at wide receiver moving forward.
Waddle departed in the third quarter and was deemed questionable to return with a shoulder injury but made his way back to the field in the fourth quarter, catching two additional passes on the team’s first possession with him back on the field. Expect an update on his ailment following the game.
Arroyo was injured while trying to recover a Rashid Shaheed fumble in the second quarter and was promptly escorted to the locker room with trainers helping to stabilize his arm. It appeared to be a potential wrist or shoulder injury based on how the staff helped him off the field. The second-year tight end was not targeted prior to departing and appears to be on the wrong side of questionable to return to Week 6.
The 49ers go on bye in Week 8. Shanahan says that Robinson is more likely to return after that, in time to face the Raiders in Week 9. Robinson can be stashed in injured reserve spots, if need be, but he is not a must-stash type of player. Depending on how the 49ers’ wide receiver corps looks, Robinson can likely be snagged off waivers during the bye week for those in need at the wide receiver position.
The Raiders continue managing Bowers’ practice reps early in the week, though he plays unrestrictedly on game day. The Raiders face the Bills in Week 6, likely facilitating a fantasy-friendly game environment. Bowers should be treated as the overall TE1 as usual this week.
Thomas is dealing with an ankle injury and needs more time to get healthy. The Seahawks recently signed Henry, a rookie, but evidently he will not play this evening, despite the Seahawks’ running back group being a tad thin due to injuries. The Seahawks face the Broncos on Thursday Night Football.
The quotes read a tad bit more enthusiastically than Jeanty did while speaking to media members at his locker, but this is still good to hear. Jeanty has been dealing with an ankle injury for a long time, but the team took that injury off the weekly practice report this week. He is now listed only with the foot injury after experiencing “a flare-up of plantar fasciitis” last Friday. Jeanty is a low-end RB1 against the Bills this week.
Tyler Allgeier should be rostered in 10-team leagues. The Cardinals have downplayed Love’s ankle issues, but two missed practices are not a good sign. He still has a chance to suit up in Week 6 against the Rams, but he is currently on the wrong side of questionable.
Allen remains out, and Parkinson (shoulder) remains limited. Tyler Higbee has played productively in the Rams’ No. 1 tight end role, and he should be expected to do so again this week against the Cardinals.
The Eagles’ starting center now has a chance to play in Week 6 against the Panthers. Eagles LG Landon Dickerson (knee) was also limited again, as was EDGE Jonathan Greenard (ankle).
Johnston is on track to play, but this wide receiver corps is very banged up. KeAndre Lambert-Smith (hamstring) and Brenen Thompson (quad) remained limited as well. Marquez Valdes-Scantling (ribs) upgraded to full.
McConkey is on track to once again be active on game day, but it is unclear how involved he will be. Two limited sessions are a good sign, but it would be great to see him practice fully tomorrow. In that instance, starting him as a WR2 would be far more palatable.